Desitin Daily Defense Baby Diaper Rash Cream with 13% Zinc Oxide Barrier Cream to Treat, Relieve & Prevent Diaper Rash, Hypoallergenic, Dye-, Phthalate- & Paraben-Free, 4 oz, 6 Pack
$5.98
$5.98
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Price: $5.98
(as of Oct 13, 2025 22:44:08 UTC – Details)
Use Desitin Daily Defense Diaper Rash Cream every day to soothe, treat and prevent baby diaper rash. This hypoallergenic and pediatrician-tested formula instantly forms a protective barrier on your baby’s tender skin and is clinically shown to provide diaper rash relief. The daily diaper rash cream is designed to work at the first hint of diaper rash to help heal and soothe your baby’s skin. Made with fast-acting formula containing 13% zinc oxide skin protectant, this barrier cream helps seal out wetness and provides protection from the first use. It is dermatologist-tested and free of parabens, phthalates, fragrances and dyes, so it’s gentle enough to use at every diaper change. The #1 choice of pediatricians and parents, the creamy formula goes on smoothly and wipes off easily, making Desitin Daily Defense Diaper Rash Cream your trusted partner for treating diaper rash from the first signs.
Is Discontinued By Manufacturer : No
Package Dimensions : 14.29 x 6.18 x 1.89 inches; 1.5 Pounds
Item model number : 07430000301
Date First Available : November 22, 2004
Manufacturer : Kenvue
ASIN : B000056J8B
Customer Reviews: 4.4 4.4 out of 5 stars 332 ratings var dpAcrHasRegisteredArcLinkClickAction; P.when(‘A’, ‘ready’).execute(function(A) { if (dpAcrHasRegisteredArcLinkClickAction !== true) { dpAcrHasRegisteredArcLinkClickAction = true; A.declarative( ‘acrLink-click-metrics’, ‘click’, { “allowLinkDefault”: true }, function (event) { if (window.ue) { ue.count(“acrLinkClickCount”, (ue.count(“acrLinkClickCount”) || 0) + 1); } } ); } }); P.when(‘A’, ‘cf’).execute(function(A) { A.declarative(‘acrStarsLink-click-metrics’, ‘click’, { “allowLinkDefault” : true }, function(event){ if(window.ue) { ue.count(“acrStarsLinkWithPopoverClickCount”, (ue.count(“acrStarsLinkWithPopoverClickCount”) || 0) + 1); } }); });
4-ounces of Desitin Daily Defense Baby Diaper Rash Cream that works from the first use to help soothe, treat and prevent diaper rash
From the #1 choice for diaper rash relief by Pediatricians and parents, this infant skin barrier cream instantly forms a protective layer on your baby’s skin for diaper rash relief and prevention
Made with 13% zinc oxide skin protectant, its fast-acting hypoallergenic formula helps seal out wetness to treat diaper rash from the first signs and is clinically shown to provide diaper rash relief
This diaper cream is specially formulated for babies’ tender skin and is paraben-, phthalate-, fragrance- and dye-free so it’s gentle enough to use daily at every diaper change
Its creamy formula goes on smoothly and wipes off easily, making Desitin Daily Defense Diaper Rash Cream your trusted partner for treating diaper rash from the first signs
8 reviews for Desitin Daily Defense Baby Diaper Rash Cream with 13% Zinc Oxide Barrier Cream to Treat, Relieve & Prevent Diaper Rash, Hypoallergenic, Dye-, Phthalate- & Paraben-Free, 4 oz, 6 Pack
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$5.98









Kate the Elder –
Reasonable price for what I got.
Can’t live without this. There’s a lower percentage of zinc oxide that some medical brands, but it does the job.
Dari –
Always the best
Desitin has always the best and my favorite. They work quick and effectively. No more rashes. The 5 stars also go to the great and quick shipping.
Kimore –
Does what it should
Good for protecting your little ones
jason lucas –
Don’t
Waited 3 weeks and got one four ounce tube when it was supposed to be a 6 pack.
IG’17 –
Actually works!
I used a couple other popular brands at first. One was gritty and the other became extremely oily. I’m so glad I have neither problem with Desitin. It’s smooth, thick and is great for daily use!
Kat –
Product is fine but don’t buy from amazon
They only sent me one tube instead of 6 and tried to charge me $40 for it (?????)
Alexis –
Perfect
This is the only cream we’ve used since my daughter was born and she hasn’t had a diaper rash since!
Amanda Spearman –
Diaper rash
This is the only product that works for diaper cream!! It’s great diaper cream.